Survey Finds Biodefense Researcher Anxiety over Inadvertently Violating the Select Agent Regulations

Abstract

A nationwide survey of biodefense researchers assesses the effectiveness of the select agent regulations, 42 CFR 73, which governs the handling, storage, and security of listed biological agents and toxins, in achieving their statutory goals of protecting public health and national security. Conducted in 2007 and 2008 among funded biodefense researchers, 509 PIs and Co-PIs were surveyed, with 198 responses (39%). Regulatory components are assessed and an “anxiety factor” is measured indicating high anxiety about inadvertently violating these regulations, leading to negative career impacts, potentially thwarting achieving the goals of the statute.